Razi University

Introduction: Multiple Sclerosis (MS) involves demyelination within the central nervous system, resulting in impaired nerve conduction and manifesting through specific clinical symptoms. Non-pharmacological interventions are currently employed to manage the symptoms of this disease. Therefore, the aim of this study is to investigate the effects of submaximal aerobic exercise on walking, balance, and cognitive function in middle-aged women with Multiple Sclerosis. Methodology: This study employs a quasi-experimental research method with a pretest-posttest control group design. The statistical population consists of all women with multiple sclerosis visiting rehabilitation clinics in Kermanshah County in the year 1405. hojam nemoneh barasas pishineh pajoosh ve ba estefadeh az nemoneh giri dardasteres 30 nafar( barasas naram afzar GPower ve ba dar nazar garaftan parametrehaye andazeh asar= 36/0, zarib alfa= 05/0 ve tavan azmon= 95/0) dar nazar garafteh shod. Based on the research literature and using a convenience sampling method, the sample size was set at 30 participants (determined via GPower software, considering the following parameters: effect size = 0.36, alpha = 0.05, and statistical power = 0.95). The tools used in this study included: the 10-meter walk test to measure walking speed; the 6-meter walk test to measure walking endurance; the Berg Balance Scale to measure static balance; the Timed Up and Go test to measure dynamic balance; a cognitive function test to assess cognitive abilities; the Stroop test to assess selective attention; a disability progression questionnaire to assess the degree of disability and the progression of Multiple Sclerosis; and an executive function questionnaire to assess executive abilities. Regarding inferential statistics, after confirming the normal distribution of the data using the Kolmogorov-Smirnov test, an independent t-test was employed to assess between-group differences, and a paired t-test was used to assess within-group differences. Findings: The results indicated a significant difference between the experimental and control groups regarding motor and cognitive variables. Additionally, a significant difference was observed in the experimental group from pre-test to post-test. Conclusion: Based on the findings, it is recommended that coaches and therapists utilize submaximal aerobic exercises to improve the motor and cognitive performance of patients with Multiple Sclerosis (MS).